Cetona is located on the side of the mountain bearing the same name, and conserves the characteristic structure of a Medieval hamlet, with lanes and small roads that wind up towards the Rocca (also referred to the Tower or the Fortress).
One of the best places to visit is the prehistoric settlement known as Belvedere, dating back 40,000 years, and the Civil Museum (Museo Civico) of the Prehistory of Cetona, which contains artifacts from the Paleolithic and Bronze Age.
In the building known as Pieve di San Michele Arcangelo constructed in 1155, it is possible to admire frescoes of the Sienese School, and other attributes said to have been painted by Cola Petruccioli. There are also a series of frescoes by Pinturicchio, which are conserved in the Church of SS. Trinitá.